These methods will clear the cache for a specific site. All other cached files for other sites in the browser will remain stored.
1. Open chrome and maneuver to the site encountering the Cookies/Cache-related error (most often Error 500). The click on the 'padlock' in the upper left hand corner, immediately to the left of the URL Bar.
2. Select "Cookies" from the dropdown menu.
3. Select the "Remove" option until all sites in the list above are gone. Once done the list should be empty.
4. Once this has been completed close the tab and maneuver back to the site you just removed all of the cookies from. Note that if this method doesn't work move on to Method 2 below.
Mozilla Firefox: https://support.mozilla.org/en-US/kb/how-clear-firefox-cache
Safari Mobile: https://support.apple.com/en-us/HT201265
Safari Macs: https://support.apple.com/guide/safari/clear-your-browsing-history-sfri47acf5d6/mac